- Serving North Mississippi since 1996
- Comprehensive Services including In-House Lab & Imaging Services
- Serving North Mississippi since 1996
- Comprehensive Services including In-House Lab & Imaging Services
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A physician experienced in the diagnosis and treatment of thyroid disease can detect a goiter due to Hashimoto's thyroiditis by performing a physical examination and can recognize hypothyroidism by identifying characteristic symptoms, finding typical physical signs, and doing appropriate laboratory tests.
Antithyroid antibodies
Increased antithyroid antibodies provide the most specific laboratory evidence of Hashimoto's thyroiditis, but they are not present in all cases.
TSH (thyroid-stimulating hormone or thyrotropin) test
Increased TSH level in the blood is the most accurate indicator of hypothyroidism. TSH is produced by another gland, the pituitary, Much is located in the center of the head behind the nose.
The level of TSH rises dramatically when the thyroid gland even slightly underproduces thyroid hormone, so a normal level of TSH reliably excludes hypothyroidism in patients with normal pituitary function.
Other tests
Free T4 (thyroxine)--the active thyroid hormone in the blood. A low level of free T4 is consistent with thyroid hormone deficiency. However, free T4 values in the "normal range" may actually represent thyroid hormone deficiency in a particular patient, since a high level of TSH stimulation may keep the free T4 levels "within normal limits" for many years.
Fine-needle aspiration of the thyroid--usually not necessary for most patients with Hashimoto's thyroiditis, but a good way to diagnose difficult cases and a necessary procedure if a thyroid nodule is also present.
For patients with thyroid enlargement (goiter) or hypothyroidism, thyroid hormone therapy is clearly needed, since proper dosage corrects any symptoms due to thyroid hormone deficiency and may decrease the goiter size. Treatment consists of taking a single daily tablet of levothyroxine.
Older patients who may have underlying heart disease are usually started on a low dose and gradually increased, while younger healthy patients can be started on full replacement doses at once. Thyroid hormone acts very slowly in the body, so it may take several months after treatment is started to notice improvement in symptoms or goiter shrinkage.
Because of the generally permanent and often progressive nature of Hashimoto's thyroiditis, it is usually necessary to treat it throughout one's lifetime and to realize that medicine dose requirements may have to be adjusted from time to time.
Optimal adjustment of thyroid hormone dosage, based on laboratory tests rather than symptoms, is critical, since the body is very sensitive to even small changes in thyroid hormone levels. The tablets come in over 10 different strengths, and it is essential to take them in a consistent manner every day.
If the dose is not adequate, the thyroid gland may continue to enlarge and symptoms of hypothyroidism will persist, and may be associated with increased serum cholesterol levels, which may increase the risk of atherosclerosis and heart disease.
If the dose is too strong, it can cause symptoms of hyperthyroidism, creating excessive strain on the heart and an increased risk of developing osteoporosis.
As noted above, Hashimoto's thyroiditis is a common disorder of the immune system which affects the thyroid gland. However, much less often, the immune system can also mistakenly target virtually any other part of the body, causing it to malfunction, and this tendency runs in families.
Although the majority of patients with Hashimoto's thyroiditis and their genetic family members will never experience any other auto immune condition, they do have a statistically increased risk of developing the following disorders:
Appropriate management of Hashimoto's thyroiditis requires continues care by a physician who is experienced in the treatment of this disease.
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